The Pian Del Vescovo estate is about 3 km from Massa Marittima. It can be reached as follows:

From Roma
Take the A12Rome-Civitavecchia motorway to the Civitavecchia exit. Continue on the Aurelia SS1 to the Follonica est (Follonica East) exit. From there continue on the SR439 towards Massa Marittima and follow the Marsiliana  and Centro Carapax e Cigogne signs. Then the route is as for the instructions from Genoa-La Spezia,.

From Firenze
Take the SS2 Florence-Sienna motorway to the Colle Val d’Elsa exit. Drive towards Massa Marittima and Follonica, first on the SS441  and then on the SR439. Do not take the first turning for Massa Marittima, keep to the main road for another 3 km. Turn off to the right at the second Massa Marittima turning (which is on your left) and follow the Marsiliana  and Centro Carapax e Cigogne signs.
Then see above.

From Genova
Take the Genoa-Livorno motorway to the Rosignano  exit. Continue on the Aurelia SS1 to the Follonica est (Follonica East) exit. The route on the SR449 to Massa Marittima is signposted. After just under 10 km you will see the town on a hill. Immediately after passing a large Esso garage on the right, turn off to the left and follow the Marsiliana  and Centro Carapax e Cigogne signs. After about 2 km on the SP143 you will see the Pian Del Vescovo estate on the right.

The nearest railway station is Follonica (or Campiglia).
The nearest airports are in Florence and Pisa. There is a rail connection to Follonica from there.